Best Skill Gem Setup for Path of Exile 2 Currency Gas Grenade Pathfinder

The Gas Grenade Pathfinder requires a strong five-link setup to reach its full potential. Below is the recommended configuration:

Gas Grenade: Arakali's Lust - Deadly Poison II - Elemental Armament II - Persistent Ground III - Encroaching Ground
(Swap Encroaching Ground for Elemental Focus against bosses.)
Ghost Dance: Compressed Duration II
Wind Dancer: Blind II - Maim - Magnified Area II
Despair: Heightened Curse - Prolonged Duration II - Efficiency II
Withering Presence: Prolonged Duration II - Clarity I
Toxic Domain: Escalating Poison - Deadly Poison II - Long Fuse II

Leveling Tip: Use Gas Grenade (Bursting Plague, Corrosion) with Contagion (Unleash) for smooth early progression. Against bosses, keep Explosive Grenade ready to detonate for high burst damage while layering poison clouds.

BiS Itemization for Gas Grenade Pathfinder

Unlike many endgame builds, the Gas Grenade Pathfinder isn't locked behind dozens of expensive uniques. However, a few Path of Exile 2 Items stand out as game-changers:

Plaguefinger (mandatory): Converts all hit damage into poison magnitude, significantly increasing poison scaling. A corrupted Plaguefinger with +1 socket is best-in-slot.
Main Weapon - Siege Crossbow: Provides consistent poison application and high attack speed.
Offhand Setup - Cursecarver (Wand) + Arvil's Wheel (Shield): The perfect duo for casting Despair. Look for Cursecarver with +4 to Despair and Arvil's Wheel with a high skill effect duration.

Jewels:

Prism of Belief: Prioritize one with +Gas Grenade levels for huge damage gains.
From Nothing: Ideally placed near the Chaos Inoculation keystone. This synergizes with Pure Chaos and cheap POE 2 Currency Orbs Wither Away, both enhancing poison and chaos effectiveness.